Travel Tips for Sao Tome and Principe, Updated Intl. Guide – Travel Medicine, Inc.
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Sao Tome and Principe

Capital: Sao Tome

Time Zone: 0 hours. No daylight savings time.
Tel. Country Code: 239
USADirect Tel.: 0
Electrical Standards: Electrical current is 220/50 (volts/hz). European Style Adaptor Plug. Grounding Adaptor Plug D.

World Health Organization
Travel Health Services
Country Insights
Travel Warnings
Consular Information
Foreign Commonweatlh Office


The U.S. Ambassador based in Gabon is accredited to Sao Tome on a non-resident basis.

Entry Requirements

• Passport/Visa: Valid passport and visa are required.

• HIV Test: Not required.

• Vaccinations: A yellow fever vaccination certificate is required from all travelers older than 1 year arriving from ALL COUNTRIES.

Destination Health Info for Travelers

AIDS/HIV: Incidence is presumed low, but widespread surveys have not been done.

Arboviral Fevers: Data are not available to indicate if arboviral fevers such as chikungunya, West Nile, Crimean-Congo hemorrhagic fever, and dengue are transmitted on the islands.

Cholera: This disease is active in this country. The risk of cholera, however, is extremely low in international travelers from developed countries, such as the United States and Canada. Cholera vaccine (no longer available in the US) is recommended only for travelers at high risk who work and live in highly endemic areas under less than adequate sanitary conditions.
The manufacture and availability of cholera vaccine in the United States ceased in June 2000. Many countries, including Canada, license an oral cholera vaccine.
Cholera vaccine is not "officially" required for entry into, or exit from, any country. Despite this, some countries, on occasion, require proof of cholera immunization from travelers coming from cholera-infected countries. Anticipating such a situation, travelers wish to carry a medical exemption letter from their health-care provider. If possible, it is advisable to contact the embassy or consulate at the destination country to confirm the requirement for cholera vaccination (if any) and the acceptability of a medical exemption letter.

Hepatitis: High risk. All susceptible travelers should receive hepatitis A vaccine or immune globulin prophylaxis. The hepatitis B carrier rate in the general population is estimated to exceed 10%. Vaccination against hepatitis B is recommended for healthcare workers and all long-term visitors to this country. No data is currently available on hepatitis E.

Malaria: Risk is present year-round throughout this country, including urban areas. Falciparum
malaria accounts for >85% of cases. Chloroquine-resistant falciparum malaria is reported.
Prophylaxis with atovaquone/proguanil (Malarone), mefloquine (Lariam), or doxycycline is currently recommended when traveling to malarious areas of this country.

Malaria is transmitted via the bite of an infected female Anopheles mosquito. Anopheles mosquitoes feed predominantly during the hours from dusk to dawn. All travelers should take measures to prevent evening and nighttime mosquito bites. Insect-bite prevention measures include applying a DEET-containing repellent to exposed skin, applying permethrin spray or solution to clothing and gear, and sleeping under a permethrin-treated bednet. DEET-based repellents have been the gold standard of protection under circumstances in which it is crucial to be protected against insect bites that may transmit disease. Nearly 100% protection can be achieved when DEET repellents are used in combination with permethrin-treated clothing.
NOTE: Picaridin repellents (20% formulation, such as Sawyer Picaridin or Natrapel 8-hour) are now recommended by the CDC and the World Health Organization as acceptable non-DEET alternatives to protect against malaria-transmitting mosquito bites. Picaridin is also effective and ticks and biting flies.
• You should consider the diagnosis of malaria if you develop an unexplained fever during or after being in this country.
• Long-term travelers who may not have access to medical care should bring along medications for emergency self-treatment should they develop symptoms suggestive of malaria, such as fever, chills, headaches, and muscle aches, and cannot obtain medical care within 24 hours.

Other Diseases/Hazards: Data on filariasis, loiasis, onchocerciasis, leishmaniasis, intestinal helminthic diseases, and rabies not available, but these diseases are presumed to occur. Tuberculosis and typhoid fever are considered to be endemic.

Schistosomiasis: Widely distributed throughout the island of Sao Tome. The major risk area is in the northeast between the Rio Grande and Manuel Jorge Rivers, including the capital and environs, the surrounding Agua Grande District, and the adjacent part of Mezoxi District. Travelers should avoid swimming, bathing, or wading in freshwater lakes, ponds, or streams.

Travelers' Diarrhea: High risk. Piped water supplies should be considered potentially contaminated. Outside of hotels and resorts, we recommend that you boil, filter or purify all drinking water or drink only bottled water or other bottled beverages and do not use ice cubes. Avoid unpasteurized dairy products. Do not eat raw or undercooked food, especially meat and fish. Peel all fruits.
• Good hand hygiene reduces the incidence of travelers’ diarrhea by 30%.
• A quinolone antibiotic, or azithromycin, combined with loperamide (Imodium), is recommended for the treatment of diarrhea. Diarrhea not responding to antibiotic treatment may be due to a parasitic disease such as giardiasis, amebiasis, or cryptosporidiosis.
• Seek qualified medical care if you have bloody diarrhea and fever, severe abdominal pain, uncontrolled vomiting, or dehydration.

Yellow Fever: Vaccination is required for entry. No recent yellow fever cases are reported. This country is in the Yellow Fever Endemic Zone. A valid yellow fever vaccination certificate may be required for travel to other countries in South America, Africa, the Middle East, or Asia.